A different way to treat an enlarged prostate.
Fig. 01PAE targets the prostate arteries (the small vessels supplying blood to the prostate) and reduces their flow with microscopic particles. Without its full blood supply, the prostate shrinks over the following weeks.
Benign prostatic hyperplasia (BPH) — non-cancerous prostate enlargement — affects roughly half of men by age 60 and 80% by age 80. As the prostate enlarges, it squeezes the urethra and causes the symptoms many men know all too well: frequent urination, urgency, weak stream, incomplete emptying, and getting up multiple times at night.
The traditional treatments are medications (which often cause side effects and stop working over time) or surgery (TURP, UroLift, Rezūm) — each with its own trade-offs around recovery, sexual function, and how aggressive the intervention needs to be. Prostate Artery Embolization (PAE) is a different option that fits in between.
PAE works by reducing the blood supply to the prostate. Through a fine catheter introduced through the wrist or upper thigh, microscopic particles are delivered into the small arteries feeding the prostate. The prostate then gradually shrinks over the following weeks as those vessels are reduced — relieving pressure on the urethra and improving urinary symptoms. There's no incision, no general anesthesia, no catheter to take home, and the procedure is done at major academic medical centers across the country.